What to look for in a whole body MRI

July 15, 2025
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5
 mins read
WRITTEN BY
The Prenuvo Editorial Team
MEDICAL REVIEWED BY
Dr. Vikash Modi, MD
Summary

Whole body MRI can be a powerful tool for early detection—but not all providers offer the same level of clinical precision or care. From research-grade equipment and physician-led oversight to rigorous protocols and real-world outcome data, Prenuvo is built for diagnostic integrity. If you're comparing services, here’s what to ask—and why it matters.

Not all scans are created equal. Here’s how to choose services or clinics you can trust.

Whole body MRI is one of the leading tools in early detection—capable of helping identify certain abnormalities and other serious conditions before symptoms appear, when treatment is more effective and outcomes are better. It also helps establish a clear baseline for your health—so you can monitor changes over time and make proactive decisions about your care. 

But as this tech becomes more widely available, not all services deliver the same level of precision, clinical oversight, or diagnostic value.

At Prenuvo, we’ve performed over 130K+ whole body scans and built our model with one goal in mind: giving patients a comprehensive view of their health.

If you're comparing providers, it’s important to ask the right questions. Does the company operate its own clinics? Who reads the scans? What kind of imaging equipment and protocols are used? Is there evidence of diagnostic accuracy, not just marketing stats?

Here’s what we believe matters most in a whole body MRI—so that we can help you make a better informed decision for your health.

Related: What to expect before, during, and after a whole body MRI

1. Medical leadership and oversight

Behind every high-quality MRI scan should be a team of trained professionals. 

At Prenuvo, our medical team is led by nationally recognized experts in radiology, oncology, and preventative medicine. Our Chief Medical Officer, Dr. Daniel Durand M.D., and senior leadership oversee a group of more than 150 medical professionals including 100 board-certified radiologists.

With complex scans like whole body MRI, physician leadership isn’t just important—it’s essential. It helps ensure accuracy, minimizes risk, and elevates the quality of care throughout the patient journey.

2. Research-grade equipment quality 

MRI quality isn’t just about machine strength—it’s about the protocols behind the scan.

Prenuvo uses research-grade MRI machines calibrated for whole body imaging that can be done in less than one hour at diagnostic quality. We optimize each scan across several clinical dimensions:

  • Voxel count: Higher voxel density = more anatomical detail.
  • Tissue weightings and orientations: Multiple contrasts and imaging planes improve the ability to help identify and characterize abnormalities.
  • Diffusion imaging: Adds critical information about the tissue environment to help distinguish benign from potentially harmful lesions.

While some providers use AI-based “denoising” a process to speed up scans or reduce cost, we prioritize resolution and accuracy. We believe technology should serve diagnostics—not the other way around. You can learn more about our equipment and process in this technical deep dive

3. Proven accuracy and real-world outcomes

Marketing claims are easy. Medical evidence is harder to prove—but far more important.

At Prenuvo, every scan is captured at 2K resolution, generating over 1 billion data points per exam. This level of detail powers insightful analysis and drives ongoing improvements to our internal imaging protocols and diagnostic models.

We also track and publish patient outcomes to ensure our scans deliver real-world impact. In our internal Polaris research project, we followed more than 1,000 patients over one year and found:

  • 2% had findings suggestive of cancer.
  • Of those who underwent a biopsy, ~50% had confirmed cancer.
  • Our false negative rate was just 0.2%.

We believe you deserve this level of clarity when considering a screening exam. If a provider shares detection rates without follow-up or accuracy data, it’s worth asking what that number actually means.

4. Consistency of care

A whole body MRI isn’t just a scan — it’s a system. Consistency matters. 

Prenuvo owns all of its clinics. That means we, together with our exclusively-affiliated Radiology group partners, choose and maintain our own MRI machines, hire and train our own technologists, and standardize every part of the experience. 

Other companies may partner with third-party imaging centers, which often specialize in general outpatients scans and can vary in quality by location, and do not work with exclusively-affiliated Radiology group partners. That variability can affect everything from patient experience to diagnostic outcomes. 

We believe healthcare should be consistent.

5. Dedicated specialist physicians, not “outsourced reads”

The most advanced scan means little if it’s not interpreted by the right expert.

Prenuvo radiologists are highly-experienced, reading many whole body scans per year. We perform internal quality assurance and work collaboratively amongst our Radiology group partners to improve diagnostic consistency across our teams.

Just as important: at Prenuvo, a single radiologist interprets the entire scan. That means one expert is looking at images of your body as a whole, providing a comprehensive analysis that isn’t siloed between different specialists for different parts of the body. This approach helps ensure findings aren’t missed at the intersections, and that patterns across systems are seen in full context.

In contrast, some providers may rely on external radiologists at third-party centers, where different body regions may be read in isolation.

This unified approach supports a more comprehensive and accurate interpretation, helping to reveal patterns and connections that might be missed when body regions are reviewed in isolation. 

6. Responsible use of AI

Artificial intelligence is transforming healthcare—but it should be applied carefully and transparently.

Some providers use AI tools to reduce image noise from lower-resolution scans, called “denoising.” While these techniques can shorten scan times, they may also risk filtering out subtle but clinically significant findings. Prenuvo uses deep learning techniques only during image acquisition (not post-processing), and always with human oversight.

Our approach is simple: use technology where it helps enhance diagnostic integrity—and avoid shortcuts that compromise it.

Start asking the right questions

Choosing a whole body MRI provider is about more than convenience or marketing—it’s about trust, accuracy, and clinical integrity.

At Prenuvo, we’ve made deliberate investments across every stage of care to help ensure our scans deliver meaningful insights, not just images. We invite patients to ask the same of any provider they’re considering:

  • Who oversees the care model?
  • What kind of machines are used?
  • Are protocols designed to help with early detection or for speed?
  • Who interprets the scans?
  • Is there published evidence of diagnostic accuracy?

If you’re looking for a whole body MRI that’s built on science, backed by data, and delivered by experts—we’re here for you. 

To learn more about a whole body MRI with Prenuvo, book a call with a member of our team.

FAQ

Citations

American Association for Cancer Research (2025, May 30). Noncontrast screening whole body MRI with diffusion-weighted imaging for multi cancer detection. AACRhttps://www.abstractsonline.com/pp8/#!/20273/presentation/1422

Prenuvo. (2025, May 30). 100,000 Prenuvo scans signal a historic milestone in proactive healthcare. Prenuvo.
https://prenuvo.com/blog/100-000-prenuvo-scans-signal-a-historic-milestone-in-proactive-healthcare

Prenuvo. (2025, May 30). Breaking it down: Prenuvo’s whole-body MRI screening explained. Prenuvo.
https://prenuvo.com/blog/breaking-it-down-prenuvos-whole-body-mri-screening-explained

Prenuvo. (2025, May 30). What to expect: Video. Prenuvo.
https://prenuvo.com/clinic-experience#What-to-expect-video

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